Climate Change Alters Gene–Diet Interactions: Nutrigenomics, Rising CO₂, and the Future of Human Health
C limate change is widely discussed in terms of rising temperatures, extreme weather events, and ecosystem disruption. Yet one of its most profound and least visible consequences lies at the molecular interface between food and human biology . As atmospheric carbon dioxide (CO₂) levels rise and climate stress intensifies, the nutritional composition of staple crops is changing in ways that directly influence how human genes function. These changes are not merely dietary concerns; they are genomic, immunological, metabolic, and intergenerational in nature. Despite growing evidence that climate change is reducing the micronutrient and protein content of major food crops, the biological consequences of these shifts remain underrepresented in climate and health discourse. This article addresses that gap by integrating climate science, crop physiology, nutrigenomics, epigenetics, microbiome research, and public health. It argues th...